Pharm-Rx Tacrolimus

Chemical Name: Tacrolimus

CAS Number: 109581-93-3

Ask Pharm-Rx Chemical Corp. Questions

Mark Bostel avatar

    Enhanced TDS

    Identification & Functionality

    Chemical Name
    Molecular formula
    C₄₄H₆₉NO₁₂ · H₂O
    Technologies
    Product Families
    Chemical Structure

    Pharm-Rx Tacrolimus - Chemical Structure - 1

    Definition

    Tacrolimus contains NLT 98.0% and NMT 102.0% of tacrolimus (C44H69NO12), calculated on the anhydrous and solvent-free basis.

    Applications & Uses

    Properties

    Typical Properties
    ValueUnitsTest Method / Conditions
    Molecular Weight822.03--

    Regulatory & Compliance

    FDA Disclaimer

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    USP Reference Standards

    USP Tacrolimus Related Compound A RS(E)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(E)-2-(4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21-(4H,23H)-tetrone.
    C43H69NO12 792.02(ERR 1-Sep-2021)
    USP Tacrolimus 8-epimer RS(3S,4R,5S,8S,9E,12S,14S,15R,16S,18R,19R,26aS)-8-Allyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-{(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone.
    C44H69NO12 804.03 (ERR 1-Sep-2021)
    USP Tacrolimus 8-propyl Analog RS(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-{(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-8-propyl-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone.
    C43H69NO12 792.01 and tacrolimus 8-propyl analog (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R, 19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24, 25,26,26a-Hexadecahydro-5,19-dihydroxy-3-{(E)-2- [(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-8-propyl-3H-pyrido[2,1-c][1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone.
    C44H71NO12 806.03

    Storage & Handling

    Storage Information

    Preserve in tight containers. Store at controlled room temperature.