Enhanced TDS
Identification & Functionality
- Chemical Name
- Molecular formula
- C₁₉H₂₀FNO₃ · HCl, C₁₉H₂₀FNO₃ · HCl · ½H₂O
- Technologies
- Product Families
- Chemical Structure
- Definition
Paroxetine Hydrochloride is anhydrous or contains one-half molecule of water of hydration. It contains NLT 98.5% and NMT 102.0% of paroxetine hydrochloride (C19H20FNO3 · HCl), calculated on the anhydrous and solvent-free basis.
Applications & Uses
Properties
- Typical Properties
Value Units Test Method / Conditions Molecular Weight 365.83 - - Molecular Weight 374.83 - -
Regulatory & Compliance
- FDA Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
- USP Reference Standards
USP Paroxetine Hydrochloride RS
USP Paroxetine Related Compound B RS(3S,4R)-3-[(Benzodioxol-5-yloxy)methyl]-4-phenylpiperidine hydrochloride.
C19H21NO3· HCl 347.84
USP Paroxetine Related Compound C RS(3R,4S)-3-[(Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride;Also known as (+)-trans-Paroxetine hydrochloride.
C19H20FNO3· HCl 365.83
USP Paroxetine Related Compound E RS4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridinehydrochloride.
C12H14FN · HCl 227.71
[NOTE—Paroxetine related compound E was previous identified as 1-methyl-4-(p-fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride.]
USP Paroxetine Related Compound F RS (3S,4R)-3-[(Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine.
C20H22FNO3 343.39USP Paroxetine Related Compound G RS (3SR,4RS)-3-[(Benzodioxol-5-yloxy)methyl]-4-(4′-fluorobiphenyl-4-yl)piperidine hydrochloride;Also known as(±)trans-3-[(1,3-Benzodioxol-5-yloxy) methyl]-4-(4′′-fluorophenyl-4′-phenyl)piperidine hydrochloride.
C25H24FNO3· HCl 441.93USP Paroxetine System Suitability Mixture A RS
Contains a mixture of the following three compounds: Paroxetine hydrochloride. Paroxetine related compound A: (3S,4R)-3- [(Benzodioxol-5-yloxy)methyl]-4-(4-methoxyphenyl)piperidine hydrochloride; Also known as piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-methoxyphenyl)-, hydrochloride (3S-trans)-.C20H23NO4∙HCl 377.86
Paroxetine related compound B: (3S,4R)-3-[(Benzodioxol-5-yloxy)methyl]-4-phenylpiperidine hydrochloride;
Also known as piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-phenyl-,hydrochloride (3S-trans)-.
C19H21NO3∙HCl 347.84