Pharm-Rx Irinotecan HCL

Chemical Name: Irinotecan Hydrochloride Hydrate

CAS Number: 136572-09-3

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    Enhanced TDS

    Identification & Functionality

    Molecular formula
    C₃₃H₃₈N₄O₆· HCl · 3H₂O
    Chemical Structure

    Pharm-Rx Irinotecan HCL - Chemical Structure - 1 


    Irinotecan Hydrochloride contains NLT 98.0% and NMT 102.0% of C33H38N4O6 · HCl, calculated on the anhydrous basis.

    Applications & Uses


    Typical Properties
    ValueUnitsTest Method / Conditions
    Molecular Weight623.14

    Regulatory & Compliance

    USP Reference Standards

    USP Irinotecan Hydrochloride RS
    USP Irinotecan Related Compound A RS (S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7] indolizino[1,2-b]quinoline-3,14(4H,12H)-dione.
    C20H16N2O5  364.35

    USP Irinotecan Related Compound B RS (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione.
    C22H20N2O5  392.40

    USP Irinotecan Related Compound C RS 11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl (1,4′-bipiperidine)-1′carboxylate
    C32H36N4O6· HCl  609.11

    USP Irinotecan Related Compound D RS (R)-9-[(1,4’-Bipiperidine)-1’-carbonyloxy]-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline hydrochloride, trihydrate.
    C33H38N4O6· HCl · 3 H2O  677.18

    Storage & Handling

    Storage Information

    Preserve in tight, light-resistant containers, and store at controlled room temperature.