SA0301 a probiotic designed for enhancing sleep quality and reducing stress, serves the food and nutrition markets. It contains lactobacillus plantarum, lactobacillus acidophilus, and bifidobacterium breve in its formulation, aiming to target these essential health aspects of nutrition and well-being.

Ingredient Name: Probiotic Blend

Functions: Probiotic

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    Identification & Functionality

    Features & Benefits

    Benefit Claims (Health)
    Product Background
    • Cancer, HIV/AIDS, and depression are major 21st-century diseases affecting 3% of the global population.
    • Chronic insomnia in Taiwan is prevalent at 10.7%, leading to societal and economic burdens.
    • Conventional sleep aids with side effects and dependencies have paved the way for natural and safe sleep-promoting probiotics in the healthcare market.
    • The gut microbiota, with over 100 trillion microbes, plays a vital role in immune regulation and gut-brain communication.

    Pharm-Rx SA0301 - Product Explaination- 1

    • Probiotics in the gut interact with the central nervous system, producing around 80% of the "happy hormone" serotonin.
    • This serotonin, stimulated by probiotic fermentation, relieves stress and promotes sleep through signals to the brain via the vagus nerve.


    Product Benefits
    • Research center introduces sleep-promoting probiotics that excel in producing γ-aminobutyric acid (GABA), a sleep-inducing factor.
    • The strain combination SA0301 includes Lactobacillus plantarum LPL28, Lactobacillus acidophilus TYCA06, and Bifidobacterium breve CCFM1025, known for their sleep and stress-relief benefits.
    • These strains stimulate serotonin secretion in the gut, transmitting happiness signals to the brain via the vagus nerve. A patent application is underway for this formulation.
    • Bifidobacterium breve CCFM1025 has demonstrated promising results in animal models, elevating short-chain fatty acids (SCFAs) and tryptophan levels, alleviating depression and anxiety symptoms, and altering gut microbiota.
    • Clinical studies on Major Depressive Disorder (MDD) patients revealed improved gut microbiota and tryptophan metabolism, leading to enhanced mood and better sleep.
    • Incorporate these sleep-promoting probiotics into your routine to support a healthy gut-brain connection, promote better sleep quality, and boost emotional well-being.

    Applications & Uses


    Typical Properties
    ValueUnitsTest Method / Conditions
    Viable Microorganisms Count1000 billion CFU/g

    Regulatory & Compliance

    FDA Disclaimer

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.